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NEWS! Congratulations to Lynn for the Outstanding Poster Presentation Award and Shreya for the Judge’s Choice Award for Best Short Talk.
SOBREIRA Lab
Passionate team exploring genes' architecture and function and their regulatory networks.
 GWASScatter plot of genetic variants against genomic position for GWAS, as 'Manhattan' shape peaks. |  Reporter AssaysFour circular genetic constructs for reporter assays with highlighted segments in different colors. |
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 Expression DataTwo-axis graph with scattered dots forming three clusters, representing gene expression analysis. |  Cell PhenotypingEukaryotic cell and graphical depiction of its lineage/ancestry representation for cell phenotyping. |
 Genome EditingCRISPR-Cas9 complex used in gene editing. A cloud-shaped Cas9 envelops CRISPR RNA and targets DNA. |  Genetic VariantRepresentation of genetic variants using varying-sized circles on a DNA double helix. |
 Fine MappingColorful histogram bars form two normal distribution curves for fine mapping genomic analysis. |  MouseStylized mouse profile, a common research model, showcasing head, eyes, ears, whiskers, and tail. |
 eQTLTwo-axis graph with scattered dots forming two eQTL clusters along a diagonal trendline. |  Cell ImagingA microscope for cell imaging with a flat base, vertical column, angled arm, and rotating lens. |
 Chromatin StateWrapped DNA on barrel-shaped histone proteins, enzymes, and an antibody portray chromatin states. |  3D Chromatin ConformationChromatin domains and 3D conformation interactions in the eukaryotic cell nucleus. |
 Tissue CultureA flask used in tissue culture assays is horizontally positioned with a layer of culture media. |  Research PartnersStethoscope symbolizing research partnerships, with Y-shaped tube linking ears and chest pieces. |
Our research addresses a fundamental biology question:
"How do genetic variants lead to functional changes at the molecular, cellular, and phenotypic levels?"
With an integrated approach, we study non-coding regulatory elements and their role in disease, aiming for innovative treatments and therapies to improve lives. We leverage cutting-edge tools such as data science, machine learning, single-cell analysis, disease modeling, and genetic screening in a systematic manner.
CONTACT
US
Address
Departments of Biological Chemistry
and Human Genetics
University of California
615 Charles E. Young Drive South
Los Angeles. CA 90095. USA.
Contact
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